Investigating the Relationship between Anthropometric Indices and Liver Enzymes in Employed Men and Women

Abstract

Introduction: Nowadays, metabolic syndrome (MetS) has emerged as a major public health issue that endangered the lives of numerous individuals worldwide. Many previous studies have investigated the relationship between MetS and anthropometric indices. This study focused on investigating the relationship between anthropometric indices with alkaline phosphatase (ALP), alanine aminotransferase (ALT) and aspartate aminotransferase (AST).

Methods: In this descriptive-analytical study, 108 employed men and women with an age range of 28 to 53 years were selected as participants. Anthropometric indices, including height, weight, body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and waist-to-height ratio (WHtR), were recorded. The levels of ALT, AST and ALP enzymes were measured through fasting blood samples. The results were also analyzed using SPSS version 16 and Pearson's correlation coefficient test.

Results: The results of the Pearson correlation test between anthropometric indices and liver enzymes indicated a significant positive correlation between BMI, WC, WHR and WHtR with the ALT (SGPT) enzyme (P < 0.05). Furthermore, these results showed that there was a significant positive correlation between WHR and all three enzymes ALT, AST and ALP (P < 0.05). A significant positive correlation was observed between WC and AST enzyme (P < 0.05).

Conclusion: The findings indicate that the WHR index is more effective in predicting the increase in ALT, AST and ALP enzymes in employed men and women