Investigating the Potential Use of Glycolipid Surfactants Extracted from Microbes as Anti-Aging Compounds in Cosmetic Formulations

Amir Mohammad  Bagheri; Mohammad Amin  Raeisi Estabragh; Mandana  Ohadi

doi:10.18502/ssu.v33i3.18837

Amir Mohammad Bagheri Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
Mohammad Amin Raeisi Estabragh Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.
Mandana Ohadi Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran.

DOI: https://doi.org/10.18502/ssu.v33i3.18837

Keywords: Microbial Surfactants, Glycolipid, Skin Aging.

Abstract

Introduction: Skin aging is a complex process of genetic and environmental factors, such as chemical pollution and ultraviolet radiation. There is increasing evidence that microbial surfactants can exert significant antiaging effects on the skin through various mechanisms, such as stimulating fibroblast growth, possessing high antioxidant capacity, and exhibiting desirable anti-inflammatory properties. Additionally, their biodegradable nature, high surface activity, good compatibility with the body's environment and stability against changes in temperature and pH have led to an increased interest among researchers in using these compounds for bio-medical and cosmetic-sanitary applications. The aim of this study was to investigate the potential effects of glycolipid surfactants of microbial origin as anti-aging ingredients in cosmetic-hygiene products.

Conclusion: This study examined the potential applications of key glycolipid surfactants (rhamnolipids and sophorolipids) derived from microbial sources to combat skin aging. Consequently, due to features such as high antioxidant capacity, anti-inflammatory properties, stimulation of collagen biosynthesis, modulation of the metabolism of fibroblasts, and more, these substances may serve as effective compounds to combat the aging process in cosmetic-hygiene products