Evaluation of Laboratory Factors in Patients with Covid 19 in Yazd, Maybod, and Ardakan Cities in 2020

Hadi  Zare Mehrjardi; Javad  Zavar Reza; Hamid Reza  Talebi; Mohammad Hossein  Zare Mehrjardi; Amin  Zare Mehrjardi

doi:10.18502/ssu.v31i4.13029

Hadi Zare Mehrjardi Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Javad Zavar Reza Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Hamid Reza Talebi Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mohammad Hossein Zare Mehrjardi Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Amin Zare Mehrjardi Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

DOI: https://doi.org/10.18502/ssu.v31i4.13029

Keywords: COVID19, Recovery, WBC, Test.

Abstract

Introduction: This new viral syndrome named as Coronavirus disease 2019 (COVID-19) by WHO. Some laboratory parameters change in the patients with covid-19. This study was conducted with the aim of evaluating laboratory parameters in the patients with COVID-19.

Methods: A cross-sectional-analytical study was conducted in the hospitals of Shahid Sadoughi of Yazd, Imam Jafar Sadegh of Meibod and Shahid Ziaei of Ardakan between April and May 2019. The study population was patients with Covid-19 with a positive PCR test, 275 people were included in the study using the available sampling method. The checklist of this study included demographic information, hospitalization information and test values (CBC, diff, ESR, AST, ALT, Cr, Urea, LDH, PT, PTT, INR). Data were analyzed by SPSS software version 17 and the significance level was considered less than 0.05.

Results: A significant difference was observed between the values of WBC, Lymphocyte, Neutrophil, ESR, Urea, Creatinine, LDH, AST tests in the two groups that died and recovered. Among the patients who were hospitalized in the general departments, ICU or both, a significant difference was found between the patients who recovered and those who died (P=0.000). Significantly, more number of hospitalization days and older age were observed in deceased patients (P=0.000).

Conclusion: In the present study, we came to the conclusion that in addition to increasing the level of WBC, neutrophil, urea, creatinine, LDH and AST in deceased patients, a decrease in lymphocytes was also observed and these results can be used in future crises of Covid-19