Evaluating the Effect of Atache Despigman Cream for the Treatment of Melasma

Farhad Handjnai; Maryam Sadat Sadati

doi:10.18502/ssu.v30i9.11218

Farhad Handjnai Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Maryam Sadat Sadati Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

DOI: https://doi.org/10.18502/ssu.v30i9.11218

Keywords: melasma, hydroquinone, treatment

Abstract

Introduction: Melasma is one of the common dermatologic diseases that has an effect on the patient's quality of life, therefore its treatment is important. Various medicinal and herbal compounds have been used, including creams containing hydroquinone, vitamin C, alfa hydroxy acids, arbutin, tretinoins, and sometimes combination creams are prescribed, and there is still no definite and guaranteed treatment for it. In the present experimental study, the effect of topical medicine Atache Despigman (Atache laboratorios, Spain), which contains 2% hydroquinone, vitamin C and fruit acids) in the treatment of melasma has been investigated. After two months of treatment with this medicine, from the patients' point of view, the results of spot reduction were very good 17%, good 53%, average 25%, and poor 5%, and these percentages from the doctor's point of view were 20%, 52%, 25%, and 3%, respectively. Therefore, the majority observed the effectiveness. With the examination by Dermacatch device, a decrease in pigmentation was also observed.