Comparison of the effectiveness of Aloe Vera gel with 2% Nitrofurazone ointment on the healing of superficial partial-thickness burns: A randomized clinical trial study

Parichehr Sabaghzadeh Irani; Hadi Ranjbar; Shokoh Varaei; Sanaz Bostani; Omalbanin Akbari; Maryam Askarymahani

doi:10.18502/npt.v9i1.7320

Parichehr Sabaghzadeh Irani Student Research Committee, Kerman University of Medical Sciences, Kerman, Iran
Hadi Ranjbar Mental Health Research Center, Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran
Shokoh Varaei Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
Sanaz Bostani Hormozgan University of Medical Sciences, Bandar Abbas, Iran
Omalbanin Akbari School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran
Maryam Askarymahani School of Nursing and Midwifery, Kerman University of Medical Sciences, Kerman, Iran

DOI: https://doi.org/10.18502/npt.v9i1.7320

Keywords: Aloe Vera gel; Nitrofurazone; burns; occlusive dressings; wound healing

Abstract

Background & Aim: Routine treatment of burn injuries is dressing with Nitrofurazone ointment. It has several complications, including sensitivity. Aloe Vera is a traditional treatment for wound healing. This study aimed to compare the effectiveness of Aloe Vera gel with Nitrofurazone ointment in the healing of superficial partial-thickness burns.

Methods & Materials: The present study was a split body controlled clinical trial which was carried out on 30 patients with superficial partial-thickness burns. The study was conducted in the Shafa Hospital in Kerman, Iran, in 2016. The sample was recruited from patients who had at least two burns, each burn on an alternate side of the body. On their burns, samples were allocated to two groups that received Aloe Vera gel or 2% Nitrofurazone ointment. Bates-Jensen Wound assessment tool was used to evaluate the healing of burns. Statistical analysis was conducted by SPSS-16 and using the repeated measure ANOVA.

Results: The repeated measure ANOVA showed that there was a significant change in the score of BWAT in all areas during the intervention period (p=0.001), but the trend of healing in the two groups during the intervention period was not significantly different (p=0.098).

Conclusion: Based on this study, it looks like Aloe vera gel is as effective as 2% Nitrofurazone ointment in healing wounds.