Clinical Presentations of Iranian Confirmed COVID-19 Patients at the Admission Time: A Preliminary Retrospective Study

  • Alireza Tabibzade Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  • Mohammad Amin Abbasi Department of Internal Medicine, Firoozabadi Hospital, Iran University of Medical Sciences, Tehran, Iran
  • Sajad Karampoor Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  • Mohammad Hadi Karbalaie Niya Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  • Maryam Esghaei Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  • Seyed Ali Javad Mousavi Department of Pulmonology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran
  • Hamid Zahednasab Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
  • Parastoo Yousefi Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
  • Hossein Keyvani Department of Virology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Keywords: COVID-19 Iran Naproxen SARS-CoV-2

Abstract

Background and Aims: The current preliminary study aimed to assess the clinical symptoms of the 67 Iranian COVID-19 patients and investigate the possible beneficial effects of the naproxen compared to the standard therapeutic regimen.

Materials and Methods: We assessed 67 COVID-19 patients. All COVID-19 cases were confirmed by computed tomography (CT) and real time-polymerase chain reaction tests. We evaluated the clinical symptoms of the patients at the admission time. Also, a group of 28 patients received naproxen besides their standard treatment. Clinical presentations, radiographic features, white blood cells (WBC) in peripheral blood, hemoglobin, platelets, C-reactive protein, erythrocyte sedimentation rate, blood urea nitrogen, lactate dehydrogenase, Albumin, and Creatine Phosphokinase were evaluated.

Results: The patients' clinical symptoms show that cough (89.6%) was the most repeated signed at the admission time, followed by fever at 78.7%, fatigue at 70%, and myalgia at least 64.2%. Unilateral slight ground-glass opacity was the most abundant presentation by 64.1% in CT. The laboratory assessment in patients indicates that mean WBC was 6193 ± 3258 (x106/L), and mean lymphocyte was 27.8 ± 12%. The survival rate and the hospitalization days for patients with or without the Naproxen regimen were not statistically significant.

Conclusion: The most common clinical symptoms in Iranian patients with COVID-19 at the admission time include cough, fever, fatigue, and myalgia. Based on the current study results, the survival rate and the hospitalization days for patients with or without Naproxen usage were not statistically significant. The laboratory parameters could not show any particular statistically significant differences.

Published
2021-12-22
Section
Articles