The Comparison of Susceptibility to SARS-CoV-2 Infection between Pediatric and Adults

Milad   Zandi; Saber  Soltani; Mona   Fani; Haniye   Shafipour; Samaneh  Abbasi

doi:10.18502/ijml.v8i4.8083

Milad Zandi Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Saber Soltani Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Mona Fani Department of Pathobiology and Laboratory Sciences, Faculty of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran
Haniye Shafipour Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Samaneh Abbasi Department of Microbiology, Faculty of Medicine, Abadan University of Medical Sciences, Abadan, Iran

DOI: https://doi.org/10.18502/ijml.v8i4.8083

Keywords: Adult Aging Children SARS-CoV-2 COVID-19

Abstract

SARS-CoV-2 causes coronavirus disease 2019 (COVID-19) and is responsible for the recent pandemic in the world. It has been recently recognized as a challenge for public health and a significant cause of severe illness in all age groups. Young children and older people are susceptible to SARS-CoV-2 infection. However, children usually present mild symptoms compared to adult patients. The relationship between age, severity, and COVID-19 transmission is compared to determine whether there is any reasonable relationship between age and COVID-19. It should be mentioned that some risk factors may increase the probability of developing severe COVID-19 by advancing age, such as pathophysiological changes in the respiratory system, angiotensin-converting enzyme 2 expression in the nasopharynx, and smoking. Susceptibility to SARS-CoV-2 infection is independent of age, but the mortality rate of COVID-19 depends on age.