Anti-Trichomonas Vaginalis Activity of Ethanolic Extracts of Medicago Sativa and Satureja Hortensis, In Vitro Study

Farzaneh   Mirzaei; Vahid Raissi; Aref T Teimouri; Parisa   Mousavi; Mohammad Ali  Mohaghegh; Mahdi  Dehghan Manshadi; Fateme   Zare; Bahman  Rahimi Esboei

doi:10.18502/ijml.v6i3.1397

Farzaneh Mirzaei
Vahid Raissi
Aref T Teimouri
Parisa Mousavi
Mohammad Ali Mohaghegh
Mahdi Dehghan Manshadi
Fateme Zare
Bahman Rahimi Esboei

DOI: https://doi.org/10.18502/ijml.v6i3.1397

Keywords: Medicago sativa, Satureja hortensis, Trichomonas vaginalis

Abstract

Background and Aims: Trichomonas vaginalis is a flagellated protozoa that is associated with vaginitis, cervicitis, urethritis and other vaginal disorders. Current study aimed to evaluate the anti-Trichomonas activity of Medicago sativa and Satureja hortensis, in vitro.
Materials and Methods: Ethanolic extract of Medicago sativa and Satureja hortensis were obtained by rotary evaporator. anti-Trichomonas vaginalis activities of the extracts in different concentrations were evaluated after 24, 48 and 72 hr of incubation of the cultured media.
Results and Conclusions: The data showed a significant difference between concentration and time regarding the Satureja hortensis and Medicago sativa extracts compared to the negative control (p<0.05). According to the results, the anti- trichomonas activity of the Medicago sativa and Satureja hortensis extracts may make it possible to use them in the treatment of trichomoniasis.