Ferroptosis in Autoimmune Disorders, Viral, and Bacterial Infections

Abstract

Ferroptosis is a type of cell death associated with excess intracellular iron and lipid peroxidation, distinct from other types of cell deaths by function and morphology. The role of ferroptosis in autoimmune disorders, which are related to inadequate removal of dead cells and debris, and infectious disorders like bacterial and viral infection have been discussed vastly. Overall, this review provides a comprehensive update on the role of ferroptosis in autoimmune and infectious diseases and suggests that targeting ferroptosis may have therapeutic potential for treating these diseases.