The Ameliorating Effects of Garlic (Allium Sativum) on Blood Glucose Levels and Lipid-Related Indices

Fatemeh  Samimi; Ali  Sharifi-Rigi; Sanaz  Dastghaib; Narjes  Hazar; Fatemeh  Zal; Morvarid  Siri; Nasim  Namiranian; Mohammad  Afkhami-Ardekani

doi:10.18502/ijdo.v17i2.18852

Fatemeh Samimi Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Ali Sharifi-Rigi Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz,
Sanaz Dastghaib Endocrinology and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Narjes Hazar Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Fatemeh Zal Department of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz,
Morvarid Siri Autophagy Research Center, Department of Clinical Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Nasim Namiranian Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Mohammad Afkhami-Ardekani Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

DOI: https://doi.org/10.18502/ijdo.v17i2.18852

Keywords: Garlic, Organic sulfides, Blood glucose, Lipid profile, Health benefits

Abstract

Garlic (Allium sativum L.), a culinary plant with medicinal properties, has been utilized as a traditional remedyby people worldwide for centuries. Garlic possesses a variety of health benefits, such as its antibacterial andanticancer properties, its capacity to slow the aging process and prevent obesity, its antihypertensive,antioxidative, and cardioprotective properties, and its capacity to reduce blood sugar and cholesterol. Garlicpossesses organosulfur compounds, which have been associated with advantageous and favorable impacts onhealth. This review specifically examines the therapeutic potential and molecular mechanisms of Garlic ininfluencing important processes related to the control of glucose and lipid metabolism. These effects have beenobserved in both laboratory studies and clinical trials. The processes encompassed within this category entail theexcretion of insulin, the absorption of glucose, the accumulation of glycogen, and the synthesis of lipids in theliver. The results of this study investigating the impact of Garlic on glucose and lipid regulation will deepen ourcomprehension of this fascinating natural compound. This information will be invaluable for healthcareprofessionals, researchers, and individuals seeking to prevent and treat metabolic disorders.