Obesity Epidemic is an Introduction of Type 2 Diabetes Mellitus and Alzheimer's Epidemic

Roya  Rafaiee; Seyedeh Maryam  Mousavi Bourkheili; Raheleh  Rafaiee

doi:10.18502/ijdo.v17i2.18845

Roya Rafaiee MD, Department of Internal Medicine, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
Seyedeh Maryam Mousavi Bourkheili MSc, School of Advanced Technologies in Medicine, Mazandaran University of Medical Sciences, Sari, Iran
Raheleh Rafaiee MD, Ph.D., Psychiatry and Behavioral Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran.

DOI: https://doi.org/10.18502/ijdo.v17i2.18845

Keywords: Obesity, Type 2 diabetes mellitus, Type 3 diabetes, Alzheimer's disease, Epidemic

Abstract

The global rise of obesity has increased the prevalence of type 2 diabetes mellitus (T2DM) and the risk ofAlzheimer’s disease (AD). The obesity, a key risk factor of T2DM, leads to insulin resistance, which contributesto cognitive decline and potentially AD through shared metabolic pathways. This Commentary highlights theconnection between obesity, T2DM, and AD, suggesting that lifestyle changes like weight loss anddiscontinuation of sugar consumption may help to prevent these conditions. Comprehensive public healthstrategies focusing on diet, exercise, and education are essential to reduce the growing health crisis and improvemetabolic and cognitive health globally.