Is Gender Important on Laboratory Variables and Complications in Type-2 Diabetes Mellitus?

Farzane Gholami; Akram Mehrabbeik; Haniyeh Nikkhah; Nasim Namiranian; Akram  Ghadiri-Anari; Reyhaneh Azizi

doi:10.18502/ijdo.v16i3.16321

Farzane Gholami Department of Medicine, Faculty of Medicine, International Campus, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Akram Mehrabbeik Diabetes Research Center, Sahid Sadoughi University of Medical Sciences,Yazd, Iran.
Haniyeh Nikkhah Diabetes Research Center, Sahid Sadoughi University of Medical Sciences,Yazd, Iran.
Nasim Namiranian Diabetes Research Center, Sahid Sadoughi University of Medical Sciences,Yazd, Iran.
Akram Ghadiri-Anari Diabetes Research Center, Sahid Sadoughi University of Medical Sciences,Yazd, Iran.
Reyhaneh Azizi Diabetes Research Center, Sahid Sadoughi University of Medical Sciences,Yazd, Iran.

DOI: https://doi.org/10.18502/ijdo.v16i3.16321

Keywords: Complications, Diabetes mellitus, Gender

Abstract

Objective: Type 2 Diabetes mellitus (T2DM) is the most prevent metabolic disease. Gender differences are important in the epidemiology, pathophysiology, and treatment of many diseases. The aim of this study is to investigate the gender effect on laboratory variables and complications in patients with T2DM.

Materials and Methods: In this descriptive cross-sectional study, patients with T2DM between 35 -65 years old who referred to Diabetes Research Center, Yazd, Iran during 2018-2019 were studied. Demographic features and clinical information of patients were extracted from patients' medical records. All information and variables were examined in two groups according to gender and the data were analyzed using SPSS 19.

Results: Totally, 1931 patients were enrolled in the study (988 females and 943 males). Most of the patients (68.6%) were treated with insulin. Body mass index was higher in women than in men. The variables of LDL (P= 0.029), triglyceride (P< 0.001) and retinopathy (P= 0.021), were significantly different between men and women

Conclusion: The results of this study showed there are significant differences between male and female patients with T2DM in terms of lipid profiles and retinopathy