Comorbidity of Diabetes and Covid-19 in 570 Positive Polymerase Chain Reaction Patients in Yazd-2019-2020

Kazem Ansari; Seyed Alireza Mousavi; Mohammad Cheraghipour; Zohreh AkhoundiMeybodi

doi:10.18502/ijdo.v14i3.10739

Kazem Ansari MD, Nano-Biotech Foresight Company Biotechnology Campus, Yazd Stem Cells and Regenerative Medicine Institute, Yazd, Iran.
Seyed Alireza Mousavi Assistant Professor, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Mohammad Cheraghipour MD, Islamic Azad University of Yazd, Yazd, Iran
Zohreh AkhoundiMeybodi Assistant Professor of Prevention and Control of Nosocomial Infection, Infectious Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

DOI: https://doi.org/10.18502/ijdo.v14i3.10739

Keywords: Diabetes mellitus, COVID-19, Comorbidity, Yazd

Abstract

Objective: Epidemiological evidence shows that the prevalence of patients with comorbidity of diabetes mellitus (DM), in Coronavirus disease 2019 (COVID-19) is remarkable and they have poor prognosis. We aimed to investigate the comorbidity of diabetes and covid-19 in positive Polymerase Chain Reaction people in Yazd.

Materials and Methods: This retrospective cohort study included data of 570 COVID-19 positive patients, admitted to Shahid Sadoughi Hospital in Yazd, Iran, from February2019 to May 2020, including demographic data and clinical outcome of COVID-19. Study data were analyzed using SPSS software-22 and T-test, Chi-square and a binary logistic regression model were used for modeling.

Results: Prevalence of COVID-19 patients with diabetes was 27% and the percentage of male patients was 62.6%. Additionally, duration of hospitalization significantly higher in diabetic patients (P= 0.004), need to invasive mechanical ventilation in diabetic patients was significantly higher than non-diabetic patients (P˂ 0.001)

Conclusion: DM is one of the most important comorbidity with COVID-19 patients and this comorbidity affects the severity of the disease and the outcome of patients.