Overtesting, Overdiagnosis, and Overtreatment of Thyroid Diseases: A Philosophical Approach to a Clinical Issue

Authors

  • Navid Ravan The Institute of Pharmaceutical Sciences, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  • Shahrzad Mohseni Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  • Hediyeh Alemi Hematology, Oncology and Stem Cell Transplantation Research Center, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  • Hamidreza Namazi Department of Medical Ethics and Department of History of Medicine, School of Medicine, Tehran University of Medical Science, Tehran, Iran
  • Bagher Larijani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran
  • Mahnaz Pejman Sani Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

DOI:

https://doi.org/10.18502/ijdl.v26i4.23123

Keywords:

Thyroid, Philosophy of medicine, Overtesting, Overdiagnosis, Overtreatment, Medicalization

Abstract

Background: The widespread availability of laboratory and imaging technologies has substantially increased the diagnosis of thyroid diseases in recent years. However, a considerable proportion of this trend reflects overtesting, which may in turn lead to overdiagnosis and overtreatment. Although these phenomena have been widely discussed in clinical research, their philosophical dimensions have received limited attention. This study aims to provide a philosophical analysis of overtesting, overdiagnosis, and overtreatment in thyroid diseases and to explore their broader implications.

Methods: This theoretical investigation adopts an analytical–philosophical approach. Relevant concepts were examined through the literature on thyroid diseases, philosophy of medicine, medical ethics, and medicalization. Within a philosophical framework, the relationships among overtesting, overdiagnosis, overtreatment, their underlying drivers, consequences, and potential preventive approaches were analyzed.

Results: The analysis suggests that overtesting constitutes a major pathway to overdiagnosis and overtreatment. These interconnected processes are driven by factors including defensive medicine, patient expectations, expanding diagnostic technologies, medicalization, and technology oriented conceptions of contemporary medicine. Beyond their clinical consequences, they entail ethical, psychological, social, and economic implications. The study proposes several philosophically informed approaches, such as strengthening clinical reasoning, promoting physician–patient dialogue, integrating medical humanities into medical education, and incorporating insights from the philosophy of technology.

Conclusion: Overtesting, overdiagnosis, and overtreatment should be regarded not only as clinical problems but also as conceptual and philosophical challenges concerning the nature of health, disease, and medicine. Integrating philosophical perspectives with clinical evidence may help reduce unnecessary medical interventions and support more balanced clinical guidelines for thyroid diseases.

Published

2026-11-01

Issue

Section

Articles