Reviewing the Main Cancer Therapies: Virotherapy Has a High Potential for Cancer Treatment

Abstract

In 2020, around 10 million deaths worldwide were attributed to cancer, making it one of the leading causes of mortality globally. On the other hand, a lot of money, time, and energy is spent on the treatment process of this disease. In fact, cancer is a big challenge that we have been facing for years, but there is still no method that can definitively cure this disease. For years, we have mainly used surgery, chemotherapy, and radiation therapy to treat cancer. Although many advances have been made in these methods, these methods are not a definitive cure for all types of cancer and also have many complications and impose high costs on patients. By virtue of the remarkable effectiveness of CAR-T cell therapy in the treatment of leukemia, hopes for effective treatment for various types of cancer increased, but by testing this method in solid tumors, it was found that this method has low efficiency in solid tumors. In this review article, I consider the challenges and mechanisms that cancer cells apply to resist different main therapies, and finally, by comparing the challenges of different therapies, I conclude that virus therapy has a higher potential than other methods to end the problem of cancer and become a definitive cure for cancer.