Epidemiological Study of Patients with COVID-19 in Iran (Markazi Province)

Alireza Kamali; Behnam Mahmoodieh; Mohammad Jamalian; Ahmad Amani; Alireza Jahangirifard

doi:10.18502/aacc.v7i3.6901

Alireza Kamali Department of Anesthesiology and Critical Care, Arak University of Medical Science, Arak, Iran.
Behnam Mahmoodieh Department of Anesthesiology and Critical Care, Arak University of Medical Science, Arak, Iran.
Mohammad Jamalian Faculty Member of Internal Medicine, School of Medicine, Arak University of Medical Sciences, Arak, Iran.
Ahmad Amani Infectious Diseases Research Center, Arak University of Medical Science, Arak, Iran.
Alireza Jahangirifard Chronic Respiratory Disease Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran.

DOI: https://doi.org/10.18502/aacc.v7i3.6901

Keywords: Covid-19; Epidemiology; Underlying disease; Mortality

Abstract

Background: The increasing prevalence of SARS-COV-2 infection necessitates further epidemiological studies in the field of this epidemic.

Methods: during 66 days (20/02/2020 to 01/06/2020) all patients diagnosed with SARS-COV-2 infection referred to Valiasr Hospital in Arak were monitored. Thus, based on the pre-prepared questionnaire, the information of the mentioned patients was extracted from the Hospital Information System (HIS) by the required formats and after eliminating the incomplete cases, it was aggregated based on coding (to preserve the patients' information). The results were evaluated using spss. v25 software.

Results: Out of 535 patients with SARS-COV-2 included in the study, 295 (55%) were male and 240 (45%) were female. Women with a mean age of 61.03 years were significantly (p = 0.009) at a higher age than men with a mean age of 56.59 years. Nearly 60% (304 patients) of patients had a history of underlying disease. Gender comparison of patients with a history of underlying disease infected with SARS-COV-2 infection did not show any significant difference between male and female patients. Comparison of the mean age of the improved and dead patients shows that the mean age of the dead patients with a significant difference (P <0.001) was higher than the improved subjects. This result is also true for people with a history of underlying disease (p<0.0001). The number of patients with arterial oxygen saturation <93% was significantly higher in the group of patients with a history of at least one chronic underlying disease than who did not have any chronic disease (P <0.0001). The mortality rate in ICU patients was significantly higher than those admitted to the normal ward (p < 0.0001).

Conclusion: Aging, gender, underlying diseases and arterial oxygen saturation (<93%) at the time of admission have important role in the hospitalization rate, severity of the disease and mortality in patients with COVID-19.