The Effect of Dexmedetomidine on Recovery Indicators after Rhinoplasty Surgery

Azim  Honarmand; Mehrdad  Adib; Seyed Mohammadreza  Safavi; Fatemeh Mohrezi  Nezhad

doi:10.18502/aacc.v11i3.18503

Azim Honarmand Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mehrdad Adib Department of Surgery, School of Medicine Isfahan, Isfahan, University of Medical Sciences, Isfahan, Iran.
Seyed Mohammadreza Safavi Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Fatemeh Mohrezi Nezhad Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

DOI: https://doi.org/10.18502/aacc.v11i3.18503

Keywords: Dexmedetomidine; Rhinoplasty surgery; General anesthesia; Nausea and vomiting

Abstract

Introduction: Postoperative complications are a major problem in rhinoplasty surgery. The purpose of this study is the evaluation of the effects of dexmedetomidine with different doses on various complications after surgery.

Methods: Patients (N=60) were randomly divided into 3 groups; in the first group, 1 mg/kg of dexmedetomidine was prescribed before the end of the operation, and then 0.5 mg/kg of infusion was given in recovery. In the second group, 1 mg/kg of dexmedetomidine was received, then a 0.7 mg/kg infusion, and in the third group, an equal volume infusion of normal saline and then was administered as an infusion. Finally, demographic data and the duration of surgery, anesthesia, and hospitalization in the recovery room were analyzed. Also, complications caused by surgery were evaluated.

Results: It was found that dexmedetomidine in both doses of 0.5 and 0.7 mg/kg can reduce the incidence of pain at different times in the recovery room. Also, the amount of pain medication in the dexmedetomidine groups was significantly lower compared to the N/S group (P value ≤ 0.05), and this drug caused a significant decrease in systolic and diastolic blood pressure as well as an incidence of nausea and vomiting in the dexmedetomidine groups compared to the control group (P value ≤ 0.05).

Conclusion: Administration of dexmedetomidine infusion in patients undergoing surgery can be effective in improving hemodynamic parameters and reducing pain and nausea and vomiting. Also, dexmedetomidine had an effective role in reducing the use of analgesics after surgery.