Opioid-Induced Hyperalgesia (OIH): Case Study of a Woman with Metastatic Colon Cancer

Naeemeh Dini; Zahra Jahangard- Rafsanjani; Mamak Tahmasebi

doi:10.18502/aacc.v10i1.14779

Naeemeh Dini Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Zahra Jahangard- Rafsanjani Department of Clinical Pharmacy, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Mamak Tahmasebi Cancer Research Center of Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran.

DOI: https://doi.org/10.18502/aacc.v10i1.14779

Keywords: Opioid-Induced Hyperalgesia (OIH); Cancer; Ketamine; Opioid; Methadone

Abstract

Pain is an unpleasant experience and a subjective term that is associated with tissue damage. Cancer patients experience pain for a myriad of reasons, from disease related to treatment causes and unrelated to both of these categories.

Opioids are the mainstay in the treatment of moderate to severe cancer pain. Progressive opioid dose increases can cause opioid-induced hyperalgesia (OIH).

OIH has no definite management, here we present a 47-year-old cancer patient with OIH and her management