The Effect of Oat Bran Supplement on Fasting Blood Sugar and Glycosylated Hemoglobin in Patients with Gestational Diabetes Mellitus: Single-blind Randomized Clinical Trial

Maedeh Shahzeidi; Azadeh Nadjarzadeh; Masoud Rahmanian; Amin Salehi Abarghuoei; Hossein Fallahzadeh; Mahdie Mogibian; Shima Abarguoei

doi:10.18502/jnfs.v4i1.395

Maedeh Shahzeidi
Azadeh Nadjarzadeh
Masoud Rahmanian
Amin Salehi Abarghuoei
Hossein Fallahzadeh
Mahdie Mogibian
Shima Abarguoei

DOI: https://doi.org/10.18502/jnfs.v4i1.395

Keywords: Diabetes; Pregnancy; Gestational diabetes mellitus; β-glucan; Blood glucose.

Abstract

Background: Gestational diabetes mellitus (GDM) is known as a degree of glucose intolerance that occurs for the first time during pregnancy. There is paucity of evidence regarding the effect of oat bran on GDM. Oat as a source of β-glucan can be effective in reducing the blood sugar levels. This study aimed to investigate the effect of oat bran on fasting blood sugar (FBS) and glycosylated hemoglobin (HbA1c) in patients with GDM. Method: This single-blind clinical trial was conducted on 90 pregnant women with GDM. The experimental group (EG) consumed 30 g of oat bran daily with 100 g of low-fat yogurt before lunch and dinner for 4 weeks. The control group (CG) consumed only low-fat yogurt and both groups received nutrition counseling. The present study investigated the FBS, HbA1c, and weight gain at the beginning and after four weeks of intervention. Results: Out of 90 patients, 80 completed the study. FBS decreased in the EG (P = 0.04, -2.75 ± 8.22), whereas, it increased in the CG (P = 0.003, 4.37 ± 8.72). No significant difference was observed between the two groups in terms of HbA1c levels. Weight gain was controlled more efficiently in the EG than the CG (P = 0.001). Conclusion: The use of oat bran for four weeks decreased the FBS,; whereas, it did not affect HbA1c levels. Weight gain was controlled better in the EG than the CG.